Specificity
ABS 054-24 binds human GIP (1-42).
Immunogen
Synthetic human gastric inhibitory polypeptide
Positive Species Reactivity
Human
Negative Species Reactivity
Not determined
Unit Size
200 µL: Cat. No. ABS 054-24-021 mL: Cat. No. ABS 054-24-11 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
Protein A purified
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation
Unconjugated BSA free
Storage
2-8ºC without exposure to light. No precautions necessary during handling.
Target
Human gastric inhibitory polypeptide (GIP) is a 42 amino acid peptide belonging to the glucagon-secretinfamily of peptide hormones. It is secreted by endocrine cells in the duodenal mucosa and stimulatesglucose-dependent insulin secretion as well as GLP-1 release from more distal endocrine (L) cells in theintestinal mucosa. GIP shows amino-acid sequence similarities to glucagon, GLP-1 and GLP-2 (fromapproximately 50% identity for glucagon to 30% identity for GLP-2).
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