Specificity
KSK 003-01 reacts with free as well as MHC class I associated β2M
Immunogen
Recombinant caiman β2M
Positive Species Reactivity
Caiman
Negative Species Reactivity
Not determined
Epitope Specificity
Reacts with a non-polymorphic epitope on caiman β2M
Unit Size
200 µL: Cat. No. KSK 003-01-021 mL: Cat. No. KSK 003-01-11 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification
Protein A/G purified (from culture supernatant)
Solvent
0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Conjugation
Unconjugated BSA free
Storage
4-8ºC without exposure to light. No precautions necessary during handling.
Target
β-2 microglobulin (β2M) is a 12-14 kDa subunit of the major histocompatibility complex (MHC) class I. β2M is a non-polymorphic molecule and is not involved in peptide binding but is essential for MHC assembly. β2M is also found in free form in the plasma. MHC class I is expressed on most nucleated cells in the caiman, including the red blood cells.
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